Provided that we're not playing by rules of the game (I.e. no health points, purely real) I would be able to take :
Clot - Beat it with small objects easily. Or you can shoot it.
Gorefast - Scary like **** to see IRL but nothing a gun/bow shot to the head can't fix.
Crawler - A large boot should do the job.
Siren - Guns ftw. Also, you could wear earmuffs, or be deaf and run at her like a nutter and hit her with a cricket bat.
Scrake - Big, tall guy but he still has a human's skull so a gun will solve the problem easy. Or maybe a bash to the head with a heavy object or a stab from a knife on a stick. Maybe a well-placed shot from an air rifle into the eye. It has a resistance to pain, like all the ZEDs, but they're still living things so e.g. you remove the things that make it live, they WILL die.