As a rough comparison...
The Germans were running a wide mix of armor, the bulk being Pz IV models with the longer 75mm gun, plus a good number of Panthers and some Tigers. Also good numbers of StuGs with the long 75mm guns. The Pz IV was arguably a slightly "bigger hitter" than the Shermans. The Panthers and Tigers heavily outclassed them! Here in the western theater, the Tiger is still a monster
The US were mostly equipped with the standard Shermans (medium 75mm gun) and the Stuart light tank (37mm gun). Both were rather under-gunned for facing heavier German tanks and rather lightly armored. This is partly countered by their speed across country, partly by their numbers. They soon began to field their own Tank Destroyers, equipped with the heavier guns (3"/76mm and later 90mm) to counter the heavier German armor.
The Brits (and Canadians) fielded the Sherman, plus Stuart as a base. They had also created the Sherman Va "Firefly" after their encounters with the Tiger in North Africa. This fielded a more powerful 17pdr gun - a long 76mm gun, far more capable of handling the heavier German armor. They also fielded a bunch of home-grown tanks, such as the Churchill and Valentine.
The Allies had numbers - but they tended to use them poorly in the earlier massed engagements, getting shot up by the Germans in strong defensive positions. It took a little while to learn the lessons...
In terms of a one-on-one, the Allies have to be careful. Most German armor can handle most Allied tanks face-on, although the Pz IV is relatively vulnerable too. Taking on Panthers and Tigers from the front will be suicidal
The Allies will have to use speed and maneuver to deal with the German armor, but should have numbers on their side. The Tigers are far more vulnerable from the sides and rear... but the Panther will always be hard - gang up on it! The Sherman Firefly is one ace up the Allies' sleeve - use it well!
The Americans also have an important weapon up their sleeve - the bazooka. Used wisely, it can make a mess of any German tank. Have to be brave too, of course!
Of course, watch out for the damn Krauts and their Panzerfausts!
Certainly looking forward to see how the whole thing plays out... good luck, guys!