What is the input lag on that setup?
It's 21.8ms in game mode, and just under 50ms in PC mode which is 4:4:4 chroma. The 21.8ms is actually better than any monitor I've owned since the CRT days!
Game mode drops the chroma a little, but it isn't noticeable in any game I have played thus far., Only on colored text (particularly blue red and purple).
That big monitor in PC gaming ?. Enjoy being blind before 50.
It's urban legend that how you use your eyes (reading, screens etc.) has much of an impact on vision. Most degrading vision is inherited.